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TRKB Protein (AA 32-430) (His tag)
NTRK2
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 95 % by SDS - PAGE
SDS
N° du produit ABIN5854466
Détail du produit
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Antigène
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TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Type de proteíne
Recombinant
Attributs du protein
AA 32-430
Origine
Toutes les origines à travers TRKB Protéines
Humain
Source
Toutes les sources à travers TRKB Protéines
Baculovirus infected Insect Cells
Purification/Conjugué
Cette TRKB protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
CPTSCKCSAS RIWCSDPSPG IVAFPRLEPN SVDPENITEI FIANQKRLEI INEDDVEAYV GLRNLTIVDS GLKFVAHKAF LKNSNLQHIN FTRNKLTSLS RKHFRHLDLS ELILVGNPFT CSCDIMWIKT LQEAKSSPDT QDLYCLNESS KNIPLANLQI PNCGLPSANL AAPNLTVEEG KSITLSCSVA GDPVPNMYWD VGNLVSKHMN ETSHTQGSLR ITNISSDDSG KQISCVAENL VGEDQDSVNL TVHFAPTITF LESPTSDHHW CIPFTVKGNP KPALQWFYNG AILNESKYIC TKIHVTNHTE YHGCLQLDNP THMNNGDYTL IAKNEYGKDE KQISAHFMGW PGIDDGANPN YPDVIYEDYG TAANDIGDTT NRSNEIPSTD VTDKTGREHL EHHHHHH
Pureté
> 95 % by SDS - PAGE
niveau d'endotoxine
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Autre désignation
BDNF/NT-3 growth factors receptor (NTRK2 Produits )
Synonymes
trkb Protein, trkb-b Protein, xtrkb Protein, si:ch211-220b11.1 Protein, trkB2 Protein, NTRK2 Protein, ntrk2 Protein, gp145-trkb Protein, TRKB Protein, GP145-TrkB Protein, trk-B Protein, AI848316 Protein, C030027L06Rik Protein, Tkrb Protein, trkB Protein, RATTRKB1 Protein, TRKB1 Protein, Trk-B Protein, TrkB Protein, neurotrophic receptor tyrosine kinase 2 Protein, neurotrophic receptor tyrosine kinase 2 L homeolog Protein, neurotrophic tyrosine kinase, receptor, type 2b Protein, neurotrophic receptor tyrosine kinase 2 S homeolog Protein, neurotrophic tyrosine kinase, receptor, type 2 Protein, NTRK2 Protein, ntrk2.L Protein, ntrk2b Protein, ntrk2.S Protein, ntrk2 Protein, Ntrk2 Protein
Sujet
NTRK2, also known as BDNF/NT-3 growth factors receptor, is a receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. It plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. Recombinant human NTRK2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
45.2kDa (407aa) 57-70kDa (SDS-PAGE under reducing conditions)
NCBI Accession
NP_001018074
UniProt
Q16620
Pathways
Signalisation RTK , Neurotrophin Signaling Pathway , cAMP Metabolic Process , Skeletal Muscle Fiber Development , Feeding Behaviour , Dicarboxylic Acid Transport
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