IL5RA Protein (AA 18-339) (His tag)

N° du produit ABIN5854571

Détail du produit

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Type de proteíne: Recombinant

Attributs du protein: AA 18-339

Origine: Souris

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette IL5RA protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: DLLNHKKFLL LPPVNFTIKA TGLAQVLLHW DPNPDQEQRH VDLEYHVKIN APQEDEYDTR KTESKCVTPL HEGFAASVRT ILKSSHTTLA SSWVSAELKA PPGSPGTSVT NLTCTTHTVV SSHTHLRPYQ VSLRCTWLVG KDAPEDTQYF LYYRFGVLTE KCQEYSRDAL NRNTACWFPR TFINSKGFEQ LAVHINGSSK RAAIKPFDQL FSPLAIDQVN PPRNVTVEIE SNSLYIQWEK PLSAFPDHCF NYELKIYNTK NGHIQKEKLI ANKFISKIDD VSTYSIQVRA AVSSPCRMPG RWGEWSQPIY VGKERKSLVE WHLEHHHHHH

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Autre désignation: Il5ra (IL5RA Produits)

Synonymes: MGC86517 Protein, IL5RA Protein, il5r Protein, cdw125 Protein, hsil5r3 Protein, gpIL-5ra Protein, CD125 Protein, CDw125 Protein, HSIL5R3 Protein, IL5R Protein, Il5r Protein, interleukin 5 receptor subunit alpha L homeolog Protein, interleukin 5 receptor subunit alpha Protein, interleukin 5 receptor, alpha Protein, il5ra.L Protein, IL5RA Protein, il5ra Protein, Il5ra Protein

Sujet: Il5ra, also known as interleukin-5 receptor subunit alpha, is known to regulate the development and function of eosinophils. This protein is a therapeutic target for hypereosinophilic diseases including allergic inflammations and asthma. Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells. Recombinant mouse Il5ra, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 37.8kDa (330aa) 40-57KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_032396

UniProt: P21183

Pathways: Signalistation JAK/STAT