Kallikrein 5 Protein (KLK5) (AA 67-293) (His tag)
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- Antigène Voir toutes Kallikrein 5 (KLK5) Protéines
- Kallikrein 5 (KLK5)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 67-293
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Origine
- Humain
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Source
- Baculovirus infected Insect Cells
- Purification/Conjugué
- Cette Kallikrein 5 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- ADLIINGSDC DMHTQPWQAA LLLRPNQLYC GAVLVHPQWL LTAAHCRKKV FRVRLGHYSL SPVYESGQQM FQGVKSIPHP GYSHPGHSND LMLIKLNRRI RPTKDVRPIN VSSHCPSAGT KCLVSGWGTT KSPQVHFPKV LQCLNISVLS QKRCEDAYPR QIDDTMFCAG DKAGRDSCQG DSGGPVVCNG SLQGLVSWGD YPCARPNRPG VYTNLCKFTK WIQETIQANS HHHHHH
- Pureté
- > 95 % by SDS - PAGE
- niveau d'endotoxine
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product KLK5 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- Kallikrein 5 (KLK5)
- Autre désignation
- KLK5 (KLK5 Produits)
- Synonymes
- KLK-L2 Protein, KLKL2 Protein, SCTE Protein, 1110030O19Rik Protein, KAL Protein, KALA Protein, Klk1 Protein, Klk5 Protein, RATKALA Protein, kallikrein related peptidase 5 Protein, kallikrein related-peptidase 5 Protein, kallikrein 5-like Protein, KLK5 Protein, Klk5 Protein, Klk5l Protein
- Sujet
- KLK5, also known as kallikrein-5, is one of the newly identified members of the kallikrein gene family, which is a subgroup of the serine protease enzyme family. It is highly expressed in skin, mammary gland and testis. KLK5 has been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. It is proposed that KLK5 regulates this process since it is able to self-activate in addition to activating KLK7 and KLK14. Recombinant human KLK5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Poids moléculaire
- 26.2kDa (236aa) 28-40kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_001070960
- UniProt
- Q9Y337
- Pathways
- Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling
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