1110001K16Rik Protein, 4833414B02Rik Protein, Scnb3 Protein, HSA243396 Protein, SCNB3 Protein, sodium voltage-gated channel beta subunit 3 Protein, sodium channel, voltage-gated, type III, beta Protein, SCN3B Protein, Scn3b Protein
Sujet
SCN3B, also known as sodium channel subunit beta-3, is an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. It was detected in brain, heart, kidney, lung, pancreas and skeletal muscle. It is expressed in adult mammalian skeletal muscle and can functionally couple to the skeletal muscle alpha subunit, SkM1. It associates with neurofascin through their extracellular immunoglobulin-like domain. Recombinant human SCN3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
16.8kDa (146aa) 18-28kDa (SDS-PAGE under reducing conditions)