ITGB1 Protein (AA 1-728) (His tag)
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- Antigène Voir toutes ITGB1 Protéines
- ITGB1 (Integrin beta 1 (ITGB1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-728
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Origine
- Humain
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Source
- Baculovirus infected Insect Cells
- Purification/Conjugué
- Cette ITGB1 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- QTDENRCLKA NAKSCGECIQ AGPNCGWCTN STFLQEGMPT SARCDDLEAL KKKGCPPDDI ENPRGSKDIK KNKNVTNRSK GTAEKLKPED ITQIQPQQLV LRLRSGEPQT FTLKFKRAED YPIDLYYLMD LSYSMKDDLE NVKSLGTDLM NEMRRITSDF RIGFGSFVEK TVMPYISTTP AKLRNPCTSE QNCTSPFSYK NVLSLTNKGE VFNELVGKQR ISGNLDSPEG GFDAIMQVAV CGSLIGWRNV TRLLVFSTDA GFHFAGDGKL GGIVLPNDGQ CHLENNMYTM SHYYDYPSIA HLVQKLSENN IQTIFAVTEE FQPVYKELKN LIPKSAVGTL SANSSNVIQL IIDAYNSLSS EVILENGKLS EGVTISYKSY CKNGVNGTGE NGRKCSNISI GDEVQFEISI TSNKCPKKDS DSFKIRPLGF TEEVEVILQY ICECECQSEG IPESPKCHEG NGTFECGACR CNEGRVGRHC ECSTDEVNSE DMDAYCRKEN SSEICSNNGE CVCGQCVCRK RDNTNEIYSG KFCECDNFNC DRSNGLICGG NGVCKCRVCE CNPNYTGSAC DCSLDTSTCE ASNGQICNGR GICECGVCKC TDPKFQGQTC EMCQTCLGVC AEHKECVQCR AFNKGEKKDT CTQECSYFNI TKVESRDKLP QPVQPDPVSH CKEKDVDDCW FYFTYSVNGN NEVMVHVVEN PECPTGPDLE HHHHHH
- Pureté
- > 95 % by SDS - PAGE
- niveau d'endotoxine
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product ITGB1 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- ITGB1 (Integrin beta 1 (ITGB1))
- Autre désignation
- ITGB1 (ITGB1 Produits)
- Synonymes
- CD29 Protein, FNRB Protein, GPIIA Protein, MDF2 Protein, MSK12 Protein, VLA-BETA Protein, VLAB Protein, 4633401G24Rik Protein, AA409975 Protein, AA960159 Protein, ENSMUSG00000051907 Protein, Fnrb Protein, Gm9863 Protein, gpIIa Protein, cd29 Protein, fnrb Protein, gpiia Protein, itgb1 Protein, mdf2 Protein, msk12 Protein, vla-beta Protein, vlab Protein, itgb1-a Protein, itgb1-b Protein, integrin subunit beta 1 Protein, integrin beta 1 (fibronectin receptor beta) Protein, integrin subunit beta 1 S homeolog Protein, integrin beta 1 Protein, integrin subunit beta 1 L homeolog Protein, ITGB1 Protein, Itgb1 Protein, itgb1.S Protein, LOC100009173 Protein, itgb1.L Protein
- Sujet
- ITGB1, also known as integrin beta-1 isoform 1A, is the only alpha 1 integrin family adhesion receptor, one of twelve integrins that share the beta 1 subunit, and one of four collagen binding integrins. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This protein is reported to down-regulate EGF-R signaling, increase expression of caveolin-1, reduce production of reactive oxygen species, regulate collagen expression, control MMP collagenase and gelatinase activity, and mediate the renal basement membrane disorder Alport syndrome. Recombinant human ITGB1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Poids moléculaire
- 79.4kDa (716aa) 70-100KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_002202
- UniProt
- P05556
- Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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