TNFRSF12A
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
TNFRSF12A
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
TNFRSF12A, also known as tumor necrosis factor receptor superfamily member 12A, is the sole signaling receptor for the proinflammatory cytokine TWEAK (TNFSF12). It is a Downstream Target of the TGF-b Signaling Pathway and regulates Fibroblast Activation. It promotes oxidative stress through NADPH oxidase activation in macrophages. It is responsible for TWEAK-induced proliferation of endothelial cells and angiogenesis. Recombinant human TNFRSF12A, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
32.6kDa (292aa) 28-40kDa (SDS-PAGE under reducing conditions)