FZD4
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
FZD4, also known as frizzled-4, is a 7- transmembrane glycoprotein of the Frizzled family within the G-protein coupled receptor superfamily. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. This pathways seem to involve interactions with G-proteins. It is involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Recombinant human FZD4, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
48.3kDa (428aa) 50-70kDa (SDS-PAGE under reducing conditions)