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FGFR1 Protein (AA 22-376) (His tag)
FGFR1
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 95 % by SDS - PAGE
SDS
N° du produit ABIN5854969
Détail du produit
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Antigène
Voir toutes FGFR1 Protéines
FGFR1
(Fibroblast Growth Factor Receptor 1 (FGFR1))
Type de proteíne
Recombinant
Attributs du protein
AA 22-376
Origine
Toutes les origines à travers FGFR1 Protéines
Humain
Source
Toutes les sources à travers FGFR1 Protéines
Baculovirus infected Insect Cells
Purification/Conjugué
Cette FGFR1 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
RPSPTLPEQA QPWGAPVEVE SFLVHPGDLL QLRCRLRDDV QSINWLRDGV QLAESNRTRI TGEEVEVQDS VPADSGLYAC VTSSPSGSDT TYFSVNVSDA LPSSEDDDDD DDSSSEEKET DNTKPNRMPV APYWTSPEKM EKKLHAVPAA KTVKFKCPSS GTPNPTLRWL KNGKEFKPDH RIGGYKVRYA TWSIIMDSVV PSDKGNYTCI VENEYGSINH TYQLDVVERS PHRPILQAGL PANKTVALGS NVEFMCKVYS DPQPHIQWLK HIEVNGSKIG PDNLPYVQIL KTAGVNTTDK EMEVLHLRNV SFEDAGEYTC LAGNSIGLSH HSAWLTVLEA LEERPAVMTS PLYLELEHHH HHH
Pureté
> 95 % by SDS - PAGE
niveau d'endotoxine
< 1.0 EU per 1ug of protein (determined by LAL method)
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
FGFR1
(Fibroblast Growth Factor Receptor 1 (FGFR1))
Autre désignation
FGFR1 (FGFR1 Produits )
Synonymes
FGFR Protein, fgfr Protein, X1FGFR Protein, XFGFR-1 Protein, XFGFRA2 Protein, bfgfr Protein, cek Protein, fgfr1 Protein, flg Protein, flt-2 Protein, flt2 Protein, kal2 Protein, ogd Protein, xfgfr1 Protein, CG7223 Protein, CT22273 Protein, CT39172 Protein, DFGF-R1 Protein, DFGF-R2 Protein, DFR-1 Protein, DFR1 Protein, DFR1/DFGF-R2 Protein, DPR3 Protein, DTRK(FR1) Protein, Dfr-1 Protein, Dfr1 Protein, DmHD-38 Protein, Dmel\\CG7223 Protein, Dtk1 Protein, EMS2 Protein, FGF-R2 Protein, FGFR2 Protein, FR1 Protein, Fr1 Protein, HD-38 Protein, HTL/FGFR1 Protein, Htl Protein, Tk1 Protein, dtk1 Protein, i100 Protein, i150 Protein, i79 Protein, j372 Protein, cd331 Protein, fgfbr Protein, fgfr-1 Protein, hbgfr Protein, n-sam Protein, ach Protein, cd333 Protein, cek2 Protein, fgfr-3 Protein, hsfgfr3ex Protein, jtk4 Protein, BFGFR Protein, CD331 Protein, CEK Protein, FGFBR Protein, FGFR-1 Protein, FLG Protein, FLT-2 Protein, FLT2 Protein, HBGFR Protein, HH2 Protein, KAL2 Protein, N-SAM Protein, OGD Protein, bFGF-R-1 Protein, AW208770 Protein, Eask Protein, Fgfr-1 Protein, Flt-2 Protein, Hspy Protein, FLG-1 Protein, FGFRI Protein, x1fgfr Protein, cb231 Protein, sb:cb231 Protein, fibroblast growth factor receptor Protein, fibroblast growth factor receptor 1 S homeolog Protein, basic fibroblast growth factor receptor 1 Protein, heartless Protein, fibroblast growth factor receptor 1 Protein, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog Protein, Fibroblast growth factor receptor 1 Protein, fibroblast growth factor receptor 1 L homeolog Protein, fibroblast growth factor receptor 1a Protein, FGFR Protein, fgfr Protein, fgfr1.S Protein, CpipJ_CPIJ005849 Protein, htl Protein, fgfr1 Protein, fgfr3.L Protein, FGFR1 Protein, Fgfr1 Protein, fgfr1.L Protein, fgfr1a Protein
Sujet
FGFR1, also known as fibroblast growth factor receptor 1, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. It is involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and auto-phosphorylation after ligand binding. Recombinant human FGFR1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
40.4kDa (363aa) 40-57KDa (SDS-PAGE under reducing conditions.)
NCBI Accession
NP_075598
UniProt
P11362
Pathways
Signalisation RTK , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Sensory Perception of Sound , Stem Cell Maintenance , S100 Proteins
Vus récemment
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