UBE2D2 Protein (AA 1-147)

N° du produit ABIN5855026

Détail du produit

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-147

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Séquence: MALKRIHKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD REKYNRIARE WTQKYAM

Pureté: > 95 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM MES(  pH 6.0) containing 50  mM NaCl, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Autre désignation: UBE2D2 (UBE2D2 Produits)

Synonymes: E2(17)KB2 Protein, PUBC1 Protein, UBC4 Protein, UBC4/5 Protein, UBCH5B Protein, 1500034D03Rik Protein, Ubc2e Protein, Ube2d2 Protein, ubc4 Protein, ube2d2 Protein, zgc:55886 Protein, E217kB Protein, ubiquitin conjugating enzyme E2 D2 Protein, ubiquitin-conjugating enzyme E2D 2A Protein, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2D 2 Protein, ubiquitin conjugating enzyme E2 D3 Protein, UBE2D2 Protein, Ube2d2a Protein, ube2d2 Protein, Ube2d2 Protein, UBE2D3 Protein

Sujet: UBE2D2, also known as Ubiquitin-conjugating enzyme E2 D2, is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. UBE2D2 catalyzes ubiquitination of IkB-alpha in a phosphorylation and SCFB-TRCP dependent manner. Recombinant human UBE2D2 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 16.7 kDa (147aa) Confirmed by MALDI-TOF

NCBI Accession: NP_003330

UniProt: P62837

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades