Complement C3b Protéine

N° du produit ABIN622147

Détail du produit

Antigène: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Type de proteíne: Native

Origine: Humain

Source: Human

Attributs du produit: Native Human C3b

Purification: Purified C3b from human serum

Pureté: > 90 %. By SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/ml

Buffer: Phosphate buffered saline, pH 7.2

Stock: -20 °C

Détail du antigène

Antigène: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Autre désignation: C3b (C3b Produits)

Sujet: Cleavage of the C3-alpha chain at peptide bond 77 results in production of C3a and C3b fragments. The C3b fragment is a glycoprotein composed of the modified C3-alpha chain and the intact C3-beta chain. Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes.

Poids moléculaire: 180 kDa

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling