IL-10 Protein (AA 19-178) (Fc Tag)
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- Antigène Voir toutes IL-10 (IL10) Protéines
- IL-10 (IL10) (Interleukin 10 (IL10))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 19-178
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Origine
- Humain
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Source
- CHO Cells
- Purification/Conjugué
- Cette IL-10 protéine est marqué à la Fc Tag.
- Fonction
- IL-10 (human):Fc (human) (rec.)
- Specificité
- The extracellular domain of human IL-10 (aa 19-178) is fused to the N-terminus of the Fc region of human IgG1.
- Attributs du produit
- Protein. The extracellular domain of human IL-10 (aa 19-178) is fused to the N-terminus of the Fc region of human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
- Pureté
- >98 % (SDS-PAGE)
- niveau d'endotoxine
- <0.06EU/μg protein (LAL test, Lonza).
- Top Product
- Discover our top product IL10 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized from 0.2μm-filtered solution in PBS.
- Conseil sur la manipulation
- Avoid freeze/thaw cycles.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- Antigène
- IL-10 (IL10) (Interleukin 10 (IL10))
- Autre désignation
- IL-10 (IL10 Produits)
- Synonymes
- CSIF Protein, GVHDS Protein, IL-10 Protein, IL10A Protein, TGIF Protein, Il-10 Protein, IL10X Protein, interleukin 10 Protein, IL10 Protein, Il10 Protein
- Sujet
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Alternate Names/Synonyms: Interleukin-10, Cytokine Sythesis Inhibitory Factor, CSIF
Product Description: Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
- NCBI Accession
- NP_000563
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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