cb758 Protein, trapa Protein, Ssr1 Protein, TRAPA Protein, 2510001K09Rik Protein, 6330400D04 Protein, AI159733 Protein, AI452176 Protein, SSR Protein, signal sequence receptor, alpha Protein, signal sequence receptor, alpha (translocon-associated protein alpha) Protein, signal sequence receptor subunit 1 Protein, signal sequence receptor, alpha (translocon-associated protein alpha) S homeolog Protein, ssr1 Protein, SSR1 Protein, Ssr1 Protein, ssr1.S Protein
Sujet
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Recombinant human SSR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Poids moléculaire
23.1kDa (209aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)