RDCCAS Protein, RBP Protein, RNBP Protein, rbp4 Protein, MGC54038 Protein, srbp Protein, PRBP Protein, RBPA Protein, Rbp-4 Protein, fb23c12 Protein, rbp Protein, wu:fb23c12 Protein, wu:fb58d04 Protein, wu:fb72b04 Protein, zgc:86911 Protein, retinol binding protein 4 Protein, renin binding protein Protein, retinol binding protein 4 S homeolog Protein, retinol binding protein 4 A, plasma Protein, retinol binding protein 4, plasma Protein, retinol binding protein 4 L homeolog Protein, RBP4 Protein, RENBP Protein, rbp4.S Protein, rbp4 Protein, Rbp4 Protein, RBP4A Protein, rbp4.L Protein
Sujet
RBP4, also known as retinol-binding protein 4, is the specific carrier for retinol, and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. This protein delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin and prevents its loss by filtration through the kidney glomeruli. Recombinant mouse RBP4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
22.4kDa (191aa) 18-28KDa (SDS-PAGE under reducing conditions.)