UBA2 Protein (AA 1-640) (His tag)

N° du produit ABIN6387816

Détail du produit

Antigène: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-640

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette UBA2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADLMALSRGL PRELAEAVAG GRVLVVGAGG IGCELLKNLV LTGFSHIDLI DLDTIDVSNL NRQFLFQKKH VGRSKAQVAK ESVLQFYPKA NIVAYHDSIM NPDYNVEFFR QFILVMNALD NRAARNHVNR MCLAADVPLI ESGTAGYLGQ VTTIKKGVTE CYECHPKPTQ RTFPGCTIRN TPSEPIHCIV WAKYLFNQLF GEEDADQEVS PDRADPEAAW EPTEAEARAR ASNEDGDIKR ISTKEWAKST GYDPVKLFTK LFKDDIRYLL TMDKLWRKRK PPVPLDWAEV QSQGEETNAS DQQNEPQLGL KDQQVLDVKS YARLFSKSIE TLRVHLAEKG DGAELIWDKD DPSAMDFVTS AANLRMHIFS MNMKSRFDIK SMAGNIIPAI ATTNAVIAGL IVLEGLKILS GKIDQCRTIF LNKQPNPRKK LLVPCALDPP NPNCYVCASK PEVTVRLNVH KVTVLTLQDK IVKEKFAMVA PDVQIEDGKG TILISSEEGE TEANNHKKLS EFGIRNGSRL QADDFLQDYT LLINILHSED LGKDVEFEVV GDAPEKVGPK QAEDAAKSIT NGSDDGAQPS TSTAQEQDDV LIVDSDEEDS SNNADVSEEE RSRKRKLDEK ENLSAKRSRI EQKEELDDVI ALDHHHHHH

Pureté: > 85 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Autre désignation: UBA2 (UBA2 Produits)

Synonymes: ATSAE2 Protein, EMB2764 Protein, EMBRYO DEFECTIVE 2764 Protein, F3K23.23 Protein, F3K23_23 Protein, SUMO-ACTIVATING ENZYME 2 Protein, SUMO-activating enzyme 2 Protein, ARX Protein, SAE2 Protein, AA986091 Protein, Arx Protein, Sae2 Protein, UBA1 Protein, Ubl1a2 Protein, Uble1b Protein, sae2 Protein, sae2-B Protein, uba2-a Protein, uba2-b Protein, uble1b-B Protein, sae2b Protein, uble1b Protein, wu:fi17g06 Protein, zgc:66354 Protein, SUMO1 activating enzyme subunit 2 Protein, SUMO-activating enzyme 2 Protein, ubiquitin like modifier activating enzyme 2 Protein, ubiquitin-like modifier activating enzyme 2 Protein, ubiquitin like modifier activating enzyme 2 L homeolog Protein, MICPUN_63834 Protein, MICPUCDRAFT_36729 Protein, SAE2 Protein, UBA2 Protein, Uba2 Protein, uba2.L Protein, uba2 Protein

Sujet: UBA2, also known as SUMO-activating enzyme subunit 2, is a family of small and related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. It is conjugated to a variety of molecules in the presence of the SAE1/UBA2 SUMO-activating(E1) enzyme and the UBE2I/Ubc9 SUMO-conjugating(E2) enzyme. It may represent an important mechanism to protect neurons during episodes of cerebral ischemia. Recombinant human UBA2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 72.3kDa (649aa) 70-100kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_005490

UniProt: Q9UBT2