DCXR Protein (AA 1-244) (His tag)
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- Antigène Voir toutes DCXR Protéines
- DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 1-244
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette DCXR protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MGSSHHHHHH SSGLVPRGSH MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC
- Pureté
- > 95 % by SDS - PAGE
- Biological Activity Comment
- Specific activity is > 1,800 pmol/min/ug and is defined as the amount of enzyme that oxidize 1pmole of xylitol to L-xylulose per minute at pH 10.0 at 37C.
- Top Product
- Discover our top product DCXR Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 1 mM DTT, 20 % glycerol, 50 mM NaCl
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
- Autre désignation
- DCXR (DCXR Produits)
- Synonymes
- DCR Protein, HCR2 Protein, HCRII Protein, KIDCR Protein, P34H Protein, SDR20C1 Protein, XR Protein, dcxr Protein, DCXR Protein, DER Protein, 0610038K04Rik Protein, 1810027P18Rik Protein, glb Protein, wu:fa12f09 Protein, zgc:111977 Protein, GLB Protein, dicarbonyl and L-xylulose reductase Protein, dicarbonyl/L-xylulose reductase Protein, dicarbonyl L-xylulose reductase Protein, L-xylulose reductase Protein, L-xylulose reductase, putative Protein, dicarbonyl/L-xylulose reductase L homeolog Protein, DCXR Protein, dcxr Protein, Dcxr Protein, CNL05930 Protein, NCU09041 Protein, AOR_1_494194 Protein, VDBG_02657 Protein, CGB_D1070C Protein, dcxr.L Protein
- Sujet
- Dicarbonyl/L-xylulose reductase, also known as DCXR, is an enzyme responsible for the metabolism of xylulose, converting it into xylitol. DCXR was expressed at low levels and was localized predominantly in the cytoplasmic membrane. In contrast, in virtually all grades of early-stage prostate cancer and in all chemohormonally treated cases, DCXR was strikingly overexpressed and was localized predominantly in the cytoplasm and nucleus. Recombinant human DCXR, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 28 kDa (264aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_057370
- UniProt
- Q7Z4W1
- Pathways
- Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process
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