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OGG1 Protein (AA 1-345) (His tag)
OGG1
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
N° du produit ABIN6388043
Détail du produit
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Antigène
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OGG1
(8-Oxoguanine DNA Glycosylase (OGG1))
Type de proteíne
Recombinant
Attributs du protein
AA 1-345
Origine
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Souris
Source
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Escherichia coli (E. coli)
Purification/Conjugué
Cette OGG1 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
MGSSHHHHHH SSGLVPRGSH MGSMLFRSWL PSSMRHRTLS SSPALWASIP CPRSELRLDL VLASGQSFRW KEQSPAHWSG VLADQVWTLT QTEDQLYCTV YRGDDSQVSR PTLEELETLH KYFQLDVSLA QLYSHWASVD SHFQRVAQKF QGVRLLRQDP TECLFSFICS SNNNIARITG MVERLCQAFG PRLIQLDDVT YHGFPNLHAL AGPEAETHLR KLGLGYRARY VRASAKAILE EQGGPAWLQQ LRVAPYEEAH KALCTLPGVG AKVADCICLM ALDKPQAVPV DVHVWQIAHR DYGWHPKTSQ AKGPSPLANK ELGNFFRNLW GPYAGWAQAV LFSADLRQPS LSREPPAKRK KGSKRPEG
Pureté
> 90 % by SDS - PAGE
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 30 % glycerol
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
OGG1
(8-Oxoguanine DNA Glycosylase (OGG1))
Autre désignation
Ogg1 (OGG1 Produits )
Synonymes
OGG1 Protein, zgc:158858 Protein, 8-oxoguanine-DNA glycosylase 1 Protein, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 Protein, ATOGG1 Protein, F8K7.14 Protein, F8K7_14 Protein, 19.m02329 Protein, DDBDRAFT_0184479 Protein, DDBDRAFT_0233024 Protein, DDB_0184479 Protein, DDB_0233024 Protein, ogg1 Protein, Tb04.1H19.930 Protein, HMMH Protein, HOGG1 Protein, MUTM Protein, OGH1 Protein, Mmh Protein, 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA glycosylase L homeolog Protein, 8-oxoguanine-DNA glycosylase 1 Protein, 8-OXOGUANINE DNA GLYCOSYLASE Protein, putative 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA-glycosylase Protein, N-glycosylase/DNA lyase OGG1 Protein, 8-oxoguanine DNA-glycosylase 1 Protein, OGG1 Protein, ogg1.L Protein, ogg1 Protein, ECU08_0770 Protein, CA_C2707 Protein, BBOV_I004290 Protein, Smp_074010.1 Protein, LOC9329243 Protein, Tb927.4.2480 Protein, Ogg1 Protein
Sujet
Ogg1, also known as N-glycosylase/DNA lyase, is a DNA glycosylase enzyme involved in base excision repair. This protein is the primary enzyme responsible for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen species (ROS). It has a beta lyase activity that nicks DNA 3 to the lesion. Recombinant mouse Ogg1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography
Poids moléculaire
41.3 kDa (368aa) Confirmed by MALDI-TOF
NCBI Accession
NP_035087
UniProt
O08760
Pathways
Réparation de l'ADN
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