Integrin beta 4 Protein (ITGB4) (AA 28-710) (His tag)

N° du produit ABIN6388181

Détail du produit

Antigène: Integrin beta 4 (ITGB4)

Type de proteíne: Recombinant

Attributs du protein: AA 28-710

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette Integrin beta 4 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPRVKFSRS ADAPAYQQGQ NQLYNELNLG RREEYDVLDK RRGRDPEMGG KPQRRKNPQE GLYNELQKDK MAEAYSEIGM KGERRRGKGH DGLYQGLSTA TKDTYDALHM QALPPRHHHH HH

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: Liquid. 20  mM Tris-HCl buffer (  pH 6.8) containing 50 % glycerol, 1  mM DTT, 1  mM EDTA, 0.1M NaCl

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Integrin beta 4 (ITGB4)

Autre désignation: ITGB4 (ITGB4 Produits)

Synonymes: AA407042 Protein, C230078O20 Protein, CD104 Protein, integrin subunit beta 4 Protein, integrin beta 4 Protein, ITGB4 Protein, Itgb4 Protein

Sujet: CD247, also known as T-cell surface glycoprotein CD3 zeta chain isoform 1, belongs to CD3Z / FCER1G family. The T cell receptor Zeta together, with alpha / beta and gamma / delta heterodimers. This Protein plays an important role in binding antigen recognition to multiple intracellular signaling pathways and also plays a role in assembly and expression of the TCR complex. Defects in CD247 defects can cause immune deficiencies. Immune deficiency, characterized by T cells, impaired immune responses to allogeneic antigens, tetanus toxoid and mitogen. Recombinant human CD247, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 14.1kDa (122aa) 13.5-18kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_932170

UniProt: P20963

Pathways: Integrin Complex