Human Ubquitin-conjugating enzyme 7(UbcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-kappa B maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes(E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human UBE2L1-UBE2L4 gene could potentially encode different isoforms of the UbcH7. UBE2L3 gene, located at chromosome 22q11.2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of UbcH7. UbcH7(154amino acid) was over-expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: UBE2G1, UBE2G, Ubc7 (Ubiquitin Conjugating enzyme 7), EC 6.3.2.19, Ubiquitin-protein ligase G1, Ubiquitin carrier protein G1, E217K, UBC7, Ubiquitin-conjugating enzyme E2 G1, Ubiquitin-conjugating enzyme E2L 3 UBC 7, UBC7 homolog yeast, UBE 2G, Ubiquitin conjugating enzyme E2 G1, Ubiquitin conjugating enzyme E2G 1 (homologous to C, elegans UBC7), Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog C, elegans) antibody, Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog yeast), Ubiquitin conjugating enzyme E2G 1, Ubiquitin protein ligase G1,. NCBI no.: NP_003338