PIG4 Protein, SAA Protein, SAA2 Protein, TP53I4 Protein, zgc:103580 Protein, saa Protein, SAA1 Protein, Saa-1 Protein, Saa2 Protein, serum amyloid A1 Protein, serum amyloid A Protein, serum amyloid A protein Protein, serum amyloid A-3 Protein, HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 Protein, serum amyloid A2 Protein, serum amyloid A 1 Protein, SAA1 Protein, saa Protein, LOC476879 Protein, SAA Protein, SAA3 Protein, HPS5 Protein, SAA2 Protein, Saa1 Protein, LOC100270725 Protein
Sujet
Serum amyloid A1(SAA1) protein is made primarily in the liver and circulates in low levels in the blood. This protein appears to play a role in the immune system. Levels of this protein increase in the blood and other tissues under conditions of inflammation. SAA1 may help repair damaged tissues, acts as an antibacterial agent, and signal the migration of germ-fighting cells to sites of infection. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid arthritis. Recombinant Serum amyloid A protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SAA1, PIG4, TP53I4, Amyloid fibril protein AA, Amyloid protein A, MGC111216, SAA, SAA2, Serum amyloid A protein precursor, Serum amyloid A1 isoform 1, Serum amyloid A1 isoform 2, Tumor protein p53 inducible protein 4. NCBI no.: AAI_05797