TCL1A Protein (AA 1-114)
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- Antigène Voir toutes TCL1A Protéines
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-114
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- TCL1A, 1-114 aa, Human, Recombinant, E.coli
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TCL1A Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 50mM Tris-HCl buffer (pH7.5) containing 10% glycerol
- Stock
- 4 °C
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- Antigène
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- Autre désignation
- TCL1A (TCL1A Produits)
- Synonymes
- TCL1A Protein, Tcl1a Protein, TCL1 Protein, Tcl1 Protein, T-cell leukemia/lymphoma 1A Protein, T cell lymphoma breakpoint 1 Protein, TCL1A Protein, Tcl1 Protein, Tcl1a Protein
- Sujet
- TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TCL1, TCL-1, protein p14TCL1, Oncogene TCL1, T-cell leukemia/lymphoma 1A anti TCL1A, P14 TCL1, P14 TCL1 protein, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, TCL 1 protein, TCL1 oncogene, TCL1 PEN, TCL1A, TCL1A. NCBI no.: NP_001092195
- Poids moléculaire
- 13.4 kDa (114aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Stem Cell Maintenance
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