LAT2 Protein (AA 27-243) (His tag)

N° du produit ABIN666998

Détail du produit

Antigène: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Type de proteíne: Recombinant

Attributs du protein: AA 27-243

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LAT2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: NTAL, 27-243aa, Human, His tag, E.coli

Pureté: > 80 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol

Stock: 4 °C

Détail du antigène

Antigène: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Autre désignation: NTAL (LAT2 Produits)

Synonymes: LAB Protein, NTAL Protein, WBSCR15 Protein, WBSCR5 Protein, WSCR5 Protein, LAT2 Protein, MGC139435 Protein, Ntal Protein, Wbscr5 Protein, AW125574 Protein, Wbscr15 Protein, linker for activation of T-cells family member 2 Protein, linker for activation of T cells family, member 2 Protein, LAT2 Protein, Lat2 Protein

Sujet: NTAL (non-T cell activation linker), as known as LAT2, is transmembrane adaptor protein (TRAP) associated with glycolipid-enriched membrane fractions (GEM or lipid rafts). This protein is primarily expressed in spleen and hematopoietic cells, such as B cells, mast cells, NK cells, and monocytes, but not resting T cells. Defects in NTAL may be a cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS). Recombinant human NTAL, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: LAT2, HSPC046, LAB, WBSCR15, WBSCR5, WSCR5, Non-T-cell activation linker LAB, Lat2, Linker for activation of B cells, Linker for activation of T cells family member 2, Membrane associated adapter molecule, Non T cell activation linker, WBSCR 5, Wbscr15, Williams Beuren syndrome chromosome region 15, Williams Beuren syndrome chromosome region 5. NCBI no.: NP_115853

Poids moléculaire: 26.2 kDa (238aa), confirmed by MALDI-TOF

Pathways: Fc-epsilon Receptor Signaling Pathway, BCR Signaling