EDF1 Protein (AA 1-148) (His tag)

N° du produit ABIN667169

Détail du produit

Antigène: EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-148

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette EDF1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: EDF1, 1-148aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))

Autre désignation: EDF1 (EDF1 Produits)

Synonymes: edf-1 Protein, mbf1 Protein, EDF-1 Protein, MBF1 Protein, 0610008L11Rik Protein, AA409425 Protein, CAP-19 Protein, zgc:73192 Protein, zgc:86829 Protein, endothelial differentiation related factor 1 S homeolog Protein, endothelial differentiation related factor 1 Protein, endothelial differentiation-related factor 1 Protein, Mbf1p Protein, edf1.S Protein, EDF1 Protein, Edf1 Protein, edf1 Protein, MBF1 Protein

Sujet: Endothelial differentiation-related factor 1, also known as EDF1 may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. Also, EDF1 binds calmodulin thorough its IQ domain and regulates nitric oxide synthase activity through calmodulin sequestration in the cytoplasm. Though ubiquitously expressed, EDF1 is most abundant in adult liver, heart, adipose tissues, intestine and pancreas. Recombinant human EDF1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EDF-1, MBF1, Endothelial differentiation-related factor 1. NCBI no.: NP_003783

Poids moléculaire: 17.4 kDa (156aa) confirmed by MALDI-TOF