PMM2 Protein (AA 1-246) (His tag)
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- Antigène Voir toutes PMM2 Protéines
- PMM2 (Phosphomannomutase 2 (PMM2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-246
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PMM2 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- PMM2, 1-246aa, Human, His tag, E.coli
- Pureté
- > 95 % by SDS – PAGE
- Top Product
- Discover our top product PMM2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
- Stock
- 4 °C
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- Antigène
- PMM2 (Phosphomannomutase 2 (PMM2))
- Autre désignation
- PMM2 (PMM2 Produits)
- Synonymes
- cb626 Protein, zgc:56149 Protein, MGC82869 Protein, pmm2 Protein, CDG1 Protein, CDG1a Protein, CDGS Protein, PMI Protein, PMI1 Protein, PMM 2 Protein, AI585868 Protein, C86848 Protein, phosphomannomutase 2 Protein, phosphomannomutase 2 S homeolog Protein, pmm2 Protein, PMM2 Protein, pmm2.S Protein, PTRG_02815 Protein, Tsp_00480 Protein, Pmm2 Protein
- Sujet
- PMM2, also known as Phosphomannomutase 2, belongs to the eukaryotic PMM family. PMM2 is involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. It catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mutations in PMM2 are associated with Congenital disorders of glycosylation (CDG)-Ia, an autosomal recessive disorder characterized by central nervous system dysfunction and multiorgan failure. Recombinant human PMM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CDG1, CDG1a, CDGS, Phosphomannomutase 2. NCBI no.: NP_000294
- Poids moléculaire
- 30.2 kDa (266aa), confirmed by MALDI-TOF
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