×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
CrkL Protein (pTry207) (His tag)
CRKL
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS – PAGE
SDS
Détail du produit
(cache)
Antigène
Voir toutes CrkL (CRKL) Protéines
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Type de proteíne
Recombinant
Attributs du protein
pTry207
Origine
Toutes les origines à travers CrkL Protéines
Humain
Source
Toutes les sources à travers CrkL Protéines
Escherichia coli (E. coli)
Purification/Conjugué
Cette CrkL protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Attributs du produit
CRKL, 1-303aa, Human, His tag, E.coli
Pureté
> 90 % by SDS – PAGE
Alternatives
(show)
Information d'application
(cache)
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
1 mg/ml (determined by Bradford assay)
Buffer
Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
Stock
4 °C
Détail du antigène
(cache)
Antigène
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Autre désignation
CRKL (CRKL Produits )
Synonymes
CRKL Protein, wu:fa55g05 Protein, wu:fj60e01 Protein, zgc:63469 Protein, 1110025F07Rik Protein, AA589403 Protein, AI325100 Protein, Crkol Protein, CRK like proto-oncogene, adaptor protein Protein, v-crk avian sarcoma virus CT10 oncogene homolog-like Protein, CRKL Protein, crkl Protein, Crkl Protein
Sujet
CRKL is a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substitutete of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and has oncogenic potential. Recombinant human CRKL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Crk-like protein,. NCBI no.: NP_005198
Poids moléculaire
35.9 kDa (323aa), confirmed by MALDI-TOF
Pathways
Interferon-gamma Pathway , Neurotrophin Signaling Pathway , Signaling of Hepatocyte Growth Factor Receptor
Vus récemment
(cache)