RGS10
Origine: Souris
Hôte: Tobacco (Nicotiana tabacum)
Recombinant
> 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
MGC82511 Protein, RGS10 Protein, 2310010N19Rik Protein, regulator of G-protein signaling 10 Protein, regulator of G-protein signaling 10 L homeolog Protein, regulator of G protein signaling 10 Protein, regulator of G-protein signalling 10 Protein, RGS10 Protein, rgs10.L Protein, rgs10 Protein, Rgs10 Protein
Sujet
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10(RGS10) belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. RGS10 protein is localized in the nucleus. Recombinant human RGS10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Regulator of G-protein signaling 10, Regulator of G protein signaling 10. NCBI no.: NP_001005339