MAT1A Protein (AA 1-395) (His tag)
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- Antigène Voir toutes MAT1A Protéines
- MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-395
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette MAT1A protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- MAT1A, 1-395aa, Human, His tag, E.coli
- Pureté
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product MAT1A Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1M NaCl, 10% glycerol
- Stock
- 4 °C
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- Antigène
- MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
- Autre désignation
- MAT1A (MAT1A Produits)
- Synonymes
- MAT Protein, MATA1 Protein, SAMS Protein, SAMS1 Protein, AdoMet Protein, SADE Protein, SAS Protein, AI046368 Protein, Ams Protein, wu:fi35e01 Protein, zgc:55442 Protein, methionine adenosyltransferase 1A Protein, methionine adenosyltransferase I, alpha Protein, MAT1A Protein, Mat1a Protein, mat1a Protein
- Sujet
- MAT1A catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. MAT1A expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT2A present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NFkappaB and TNFalpha cause a switch from MAT1A to MAT2A expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth. Recombinant human MAT1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: MAT, MATA1, SAMS, SAMS1, methionine adenosyltransferase I alpha, S-adenosylmethionine synthetase, MAT1A,. NCBI no.: NP_000420
- Poids moléculaire
- 45.6 kDa (414aa), confirmed by MALDI-TOF.
- Pathways
- Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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