PYCR1 Protein (AA 1-319) (His tag)

N° du produit ABIN667842

Détail du produit

Antigène: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-319

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PYCR1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PYCR1, 1-319aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.5) containing 10% Glycerol

Stock: 4 °C

Détail du antigène

Antigène: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Autre désignation: PYCR1 (PYCR1 Produits)

Synonymes: arcl2b Protein, p5c Protein, p5cr Protein, pig45 Protein, pp222 Protein, pro3 Protein, pycr Protein, ARCL2B Protein, ARCL3B Protein, P5C Protein, P5CR Protein, PIG45 Protein, PP222 Protein, PRO3 Protein, PYCR Protein, zgc:73112 Protein, pyrroline-5-carboxylate reductase family, member 1 L homeolog Protein, pyrroline-5-carboxylate reductase 1 Protein, pyrroline-5-carboxylate reductase 1a Protein, pycr1.L Protein, PYCR1 Protein, Pycr1 Protein, pycr1a Protein

Sujet: PYCR1 is a universal housekeeping enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. It forms a homopolymer and localizes to the mitochondrion. Defects in PYCR1 are the cause of cutis laxa autosomal recessive type 2B (ARCL2B). Recombinant human PYCR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Pyrroline-5-carboxylate reductase 1, ARCL2B, P5C, P5CR, PIG45, PP222, PRO3. NCBI no.: NP_008838

Poids moléculaire: 35.5 kDa(339aa), confirmed by MALDI-TOF