Follistatin Protein (FST)
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- Follistatin (FST)
- Type de proteíne
- Recombinant
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Origine
- Souris
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- N° du produit (Fournisseur)
- 010-001-u88-0005
- Fournisseur
- Rockland
- Fonction
- Mouse Follistatin Recombinant Protein
- Purification
- Follistatin purity was determined to be greater than 90% as determined by analysis by reducing and non-reducing SDS-pAGE.
- Pureté
- 90,00%
- niveau d'endotoxine
- Measured by LAL is typically ≤ 1 EU/μg protein.
- Biological Activity Comment
- The activity is determined by the dose-dependent neutralization of 7.5 ng/mL human Activin A. Complete neutralization is typically reached at less than 0.3 ug/mL.
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- Discover our top product FST Protéine
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- Indications d'application
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Other: User Optimized
Application_Note: Follistatin Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Follistatin in immunological assays.
- Commentaires
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Suggested_Applications: Cellular Assay
Other_Performance_Data:
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 5 μL (5-50 μL)
- Buffer
- Buffer Formulation: 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5.
- Agent conservateur
- Without preservative
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
- Date de péremption
- 6 months
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- Antigène
- Follistatin (FST)
- Autre désignation
- Fst (FST Produits)
- Sujet
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Synonyms: FS, activin-binding protein, FSH-suppressing protein (FSP)
Background: Follistatin is an autocrine acting protein that is expressed by many tissues, but at noteably higher levels in the ovary and skin. Follistatin functions to negatively regulate the signaling of a wide variety of TGF-beta family members (activin, BMPs, myostatin, GDF-11 and TGF-beta 1). Mechanistically, follistatin works as an antagonist by complexing with TGF-beta family members to prevent them from interacting with their signaling receptors. Recombinant mouse follistatin is a non-glycosylated protein, containing 289 amino acids, with a molecular weight of 31.6 kDa.
- UniProt
- P47931
- Pathways
- Negative Regulation of Hormone Secretion
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