Neuregulin 1 Protein (NRG1)

N° du produit ABIN6700298

N° du produit (Fournisseur): 009-001-w05-0010

Détail du produit

Antigène: Neuregulin 1 (NRG1)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

N° du produit (Fournisseur): 009-001-w05-0010

Fournisseur: Rockland

Fonction: Human Neuregulin 1-beta Recombinant Protein

Purification: Neuregulin 1-beta purity was determined to be greater than 95% as determined by reducing and non-reducing SDS-pAGE.

Pureté: 95,00%

niveau d'endotoxine: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the ability to stimulate proliferation of MC-7 cells under serum free conditions and is typically less than 0.3 ng/mL.

Information d'application

Indications d'application:

Other: User Optimized

Application_Note: Neuregulin 1-beta Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-Neuregulin 1-beta in immunological assays.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 10 μL (10-100 μL)

Concentration: 0.1 mg/mL

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Date de péremption: 6 months

Détail du antigène

Antigène: Neuregulin 1 (NRG1)

Autre désignation: NRG1 (NRG1 Produits)

Sujet:

Synonyms: Acetylcholine receptor-inducing activity (ARIA), Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, Neu differentiation factor, NGR beta 1, heregulin, HRG1 beta, Sensory and motor neuron-derived factor

Background: Neuregulin 1-beta (NRG1) is one of many isoforms of NRG that contains a soluble EGF-like domain. Alpha and beta varients are distinguished by difference in length at the C terminus. The EGF-like domain signals through receptors ErbB2, ErbB3, and ErbB4 to act as a growth factor. NRG isoforms are particularly important for nervous system and cardiovasucular development. Recombinant human NRG1-beta is a non-glycosylated protein, containing 66 amino acids, with a molecular weight of 7.6 kDa.

UniProt: Q02297

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation