SCYL1 Protein (GST tag)

N° du produit ABIN6700489

N° du produit (Fournisseur): 009-001-t26s

Détail du produit

Antigène: SCYL1 (SCY1-Like 1 (SCYL1))

Type de proteíne: Recombinant

Origine: Humain

Source: Insect cells (Sf9)

Purification/Conjugué: Cette SCYL1 protéine est marqué à la GST tag.

Application: Western Blotting (WB)

N° du produit (Fournisseur): 009-001-t26s

Fournisseur: Rockland

Fonction: SCYL1 recombinant protein-GST fusion protein

Purification: Recombinant human SCYL1 (1-556) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >95% by densitometry.

Pureté: >95%

Information d'application

Indications d'application:

Western_Blot_Dilution: User Optimized

Application_Note: SCYL1 Protein is suitable for use in Western Blot. Expect a band approximately ~85 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 μg/μL

Buffer: SCYL1 Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.

Stock: -80 °C

Stockage commentaire: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: SCYL1 (SCY1-Like 1 (SCYL1))

Autre désignation: SCYL1 (SCYL1 Produits)

Sujet:

Synonyms: GKLP, HT019, NKTL, NTKL, P105, TAPK, TEIF, TRAP, N-terminal kinase-like protein, Coated vesicle-associated kinase of 90 kDa, SCY1-like protein 1, Telomerase regulation-associated protein, Telomerase transcriptional element-interacting factor, Teratoma-associated tyrosine kinase

Background: SCYL1 is a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. SCYL1 has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. SCYL1 activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. SCYL1 forms multimers following transfection into COS-7 cells (1). A SCYL1 binding protein has been identified that co-localized with SCYL1 in cytoplasm and shows ubiquitous expression (2). SCYL1 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Inflammation, Invasion/Metastasis, and Neurobiology research.

NCBI Accession: NM_020680

Pathways: Signalisation p53