IL-17A/F Protéine

N° du produit ABIN6700944

N° du produit (Fournisseur): 010-001-v56-0100

Détail du produit

Antigène: IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))

Type de proteíne: Recombinant

Origine: Souris

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

N° du produit (Fournisseur): 010-001-v56-0100

Fournisseur: Rockland

Fonction: Mouse Interleukin-17AF Heterodimer Recombinant Protein

Purification: Interleukin-17AF Heterodimer purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

Pureté: 98,00%

niveau d'endotoxine: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: Measured by LAL is typically ≤ 1 EU/μg protein.

Information d'application

Indications d'application:

Other: User Optimized

Application_Note: Interleukin-17AF Heterodimer Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-Interleukin-17AF Heterodimer in immunological assays.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Date de péremption: 6 months

Détail du antigène

Antigène: IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))

Autre désignation: IL-17AF Heterodimer (IL-17A/F Produits)

Sujet:

Synonyms: IL17 heterodimer, IL17AF heterodimer, CTLA-8 ML-1 dimer, Interleukin 17AF, Interleukin-17AF heterodimer

Background: Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the IL-17R receptor, its biological function is similar to that of IL-17A in that it induces the production of a variety of chemokines, in addition to airway neutrophilia. In regard to these functions, IL-17AF has less activity than the IL-17A homodimer but, greater activity than the IL-17F homodimer. Human and rat IL-17AF both show activity on mouse cells. Recombinant mouse IL-17AF is a non-glycosylated, disulfide-linked heterodimer. It is containing one IL-17A subunit and one IL-17F subunit, with a total of 271 amino acids and an molecular weight of 30.7 kDa.

UniProt: Q62386