IL-33 Protein (AA 109-270) (His tag)
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- Antigène Voir toutes IL-33 (IL33) Protéines
- IL-33 (IL33) (Interleukin 33 (IL33))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 109-270
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL-33 protéine est marqué à la His tag.
- Séquence
- AA 109-270
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL33 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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Identification of Human Single-Domain Antibodies against SARS-CoV-2." dans: Cell host & microbe, (2020) (PubMed).
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Identification of Human Single-Domain Antibodies against SARS-CoV-2." dans: Cell host & microbe, (2020) (PubMed).
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- Antigène
- IL-33 (IL33) (Interleukin 33 (IL33))
- Autre désignation
- IL-33 (IL33 Produits)
- Synonymes
- IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
- Sujet
- Interleukin 33 (IL33) is known as C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2,and is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 mediates its biological effects by interacting with the receptors ST2 (aka IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs.
- Poids moléculaire
- 20.2 kDa
- Pathways
- Production of Molecular Mediator of Immune Response
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