CCL14 Protein (AA 28-93) (Biotin)

N° du produit ABIN6952143

Détail du produit

Antigène: CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 28-93

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CCL14 protéine est marqué à la Biotin.

Application: Cell Migration Assay (CMA)

Séquence: GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN

Attributs du produit: Biotininylated Recombinant Human CCL14 (HCC-1)

Pureté: > 97 % by SDS PAGE

niveau d'endotoxine: <0.01 EU per 1μg of the protein by the LAL method

Biological Activity Comment: EC50 = 0.2-0.4 nM determined by migration assay with cells expressing recombinant CCR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

Stock: -20 °C,-80 °C

Stockage commentaire: 12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution.

Date de péremption: 12 months

Détail du antigène

Antigène: CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

Autre désignation: CCL14 (HCC-1) (CCL14 Produits)

Synonymes: CCL14 Protein, CC-1 Protein, CC-3 Protein, CKB1 Protein, HCC-1 Protein, HCC-1(1-74) Protein, HCC-1/HCC-3 Protein, HCC-3 Protein, MCIF Protein, NCC-2 Protein, NCC2 Protein, SCYA14 Protein, SCYL2 Protein, SY14 Protein, C-C motif chemokine ligand 14 Protein, C-C motif chemokine 14 Protein, chemokine (C-C motif) ligand 14 Protein, CCL14 Protein, Ccl14 Protein, LOC480603 Protein, LOC101115044 Protein

Sujet: Hemofiltrate CC chemokine-1(HCC-1/CCL14) is endogeneously expressed by numerous tissues. Upon processing of the N terminal residues of the full length HCC-1 by the uPA-plasmin system, the active form of HCC-1 (made by ChemoTactics) is a strong agonist for CCR1, CCR5 and to a lesser extent CCR3, and causes chemotaxis of different types of leukocytes. The active form of HCC-1 is also shown as a potent inhibitor of HIV entry.

Poids moléculaire: 10.220 kDa

UniProt: Q16627