CCL19 Protein (AA 22-98) (Biotin)
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- Antigène Voir toutes CCL19 Protéines
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 22-98
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette CCL19 protéine est marqué à la Biotin.
- Application
- Cell Migration Assay (CMA)
- Séquence
- GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS
- Attributs du produit
- Biotininylated Recombinant Human CCL19 (MIP-3beta)
- Pureté
- > 97 % by SDS PAGE
- niveau d'endotoxine
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 18-25 nM determined by migration assay with cells expressing recombinant CCR7
- Top Product
- Discover our top product CCL19 Protéine
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Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 26-108) protein (His tag)
CCL19 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) (Active) proteinCCL19 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (T7 tag)CCL19 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 1-98) protein (GST tag)CCL19 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (Fc Tag)CCL19 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Stock
- -20 °C,-80 °C
- Stockage commentaire
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Date de péremption
- 12 months
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- Antigène
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- Autre désignation
- CCL19 (MIP-3beta) (CCL19 Produits)
- Synonymes
- CKb11 Protein, ELC Protein, MIP-3b Protein, MIP3B Protein, SCYA19 Protein, CCL19 Protein, Scya19 Protein, exodus-3 Protein, C-C motif chemokine ligand 19 Protein, chemokine (C-C motif) ligand 19 Protein, CCL19 Protein, ccl19 Protein, Ccl19 Protein
- Sujet
- Macrophage inflammatory protein-3-beta (MIP-3beta/CCL19), also known as EBI1 ligand chemokine (ELC), directs chemotaxis of dendritic cells, and certain B- and T- lymphocytes, but not monocytes or granulocytes. It is constituitively expressed in thymus and lymph nodes and binds specifically to target cells expressing the receptor CCR7. Being a homeostatic chemokine, its primary physiological role is considered to be in the normal recirculation and homing of lymphocyte. However, MIP-3beta could also be proinflammatory, and is implicated in the post-HIV infection responses.
- Poids moléculaire
- 11.219 kDa
- UniProt
- Q99731
- Pathways
- Positive Regulation of Immune Effector Process
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