CCL27 Protein (AA 25-112)

N° du produit ABIN6952170

Détail du produit

Antigène: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 25-112

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Cell Migration Assay (CMA)

Séquence: FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG

Attributs du produit: Recombinant Human CCL27 (CTACK)

Pureté: > 97 % by SDS PAGE

niveau d'endotoxine: <0.01 EU per 1μg of the protein by the LAL method

Biological Activity Comment: EC50 = 34 nM determined by Migration Assay in cells expressing recombinant CCR10

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

Stock: -20 °C,-80 °C

Stockage commentaire: 12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution.

Date de péremption: 12 months

Détail du antigène

Antigène: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Autre désignation: CCL27 (CTACK) (CCL27 Produits)

Synonymes: ALP Protein, ILC Protein, CTACK Protein, ESkine Protein, CCL27 Protein, CTAK Protein, ESKINE Protein, PESKY Protein, SCYA27 Protein, AW558992 Protein, Ccl27 Protein, Scya27 Protein, Scya27a Protein, C-C motif chemokine ligand 27 Protein, uncharacterized LOC508933 Protein, chemokine (C-C motif) ligand 27A Protein, Ccl27 Protein, CCL27 Protein, LOC508933 Protein, Ccl27a Protein

Sujet: Cutaneous T-cell-attracting chemokine (CTACK/CCL27) is a ligand for cell surface receptor CCR10. It is responsible for chemotaxis of skin-homing memory T cells during cutaneous inflammation. Interestingly, after CCR10-mediated internalization, CTACK, as well as a non-secreted splice variant of the same gene, can reach the nucleus and modulate transcription and cell behavior.

Poids moléculaire: 10.149kDa

UniProt: Q9Y4X3