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CCL3 Protein (AA 24-92) (Biotin)

CCL3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
N° du produit ABIN6952184
  • Antigène Voir toutes CCL3 Protéines
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 24-92
    Origine
    • 19
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    Humain
    Source
    • 24
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CCL3 protéine est marqué à la Biotin.
    Application
    Cell Migration Assay (CMA)
    Séquence
    SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
    Attributs du produit
    Biotininylated Recombinant Human CCL3 (MIP-1alpha)
    Pureté
    > 97 % by SDS PAGE
    niveau d'endotoxine
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 1.1-2.6 nM determined by Migration Assay of recombinant CCR5 containing cells
    Top Product
    Discover our top product CCL3 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Date de péremption
    12 months
  • Antigène
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Autre désignation
    CCL3 (MIP-1alpha) (CCL3 Produits)
    Synonymes
    MIP-1alpha Protein, G0S19-1 Protein, LD78ALPHA Protein, MIP-1-alpha Protein, MIP1A Protein, SCYA3 Protein, MIP-1a Protein, Scya3 Protein, AI323804 Protein, LD78alpha Protein, MIP1-(a) Protein, MIP1-alpha Protein, Mip1a Protein, CCL3L1 Protein, CCL3L3 Protein, chemokine (C-C motif) ligand 3 Protein, C-C motif chemokine ligand 3 Protein, CCL3 Protein, Ccl3 Protein
    Sujet
    Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
    Poids moléculaire
    10.135 kDa
    UniProt
    P10147
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Autophagy
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