IL8
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 85 % as determined by reducing SDS-PAGE.
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
Stock
-20 °C,-80 °C
Stockage commentaire
12 months from date of receipt, -20 to -70 °C as supplied. Suggest to use immediately after reconstitution 1 month at -20 to -70 °C under sterile conditions after reconstitution.
Interleukin 8 (IL-8 /CXCL8) is secreted primarily by macrophages and monocytes. It is one of the key mediators for inflammatory responses. IL-8 is a strong chemotractant for neutrophils and monocytes promoting activation of these cells by binding to two cell surface receptors, CXCR1 and CXCR2. It is also a strong angiogenic agent and is considered to play a role in the pathogenesis of bronchiolitis.