SARS-CoV-2 Spike S1 Protein (RBD) (Fc Tag)
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- Antigène Voir toutes SARS-CoV-2 Spike S1 Protéines
- SARS-CoV-2 Spike S1
- Type de proteíne
- Recombinant
- Attributs du protein
- RBD
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Origine
- SARS Coronavirus-2 (SARS-CoV-2)
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SARS-CoV-2 Spike S1 protéine est marqué à la Fc Tag.
- Séquence
- AA 319-541
- Attributs du produit
- 2019-nCoV (COVID-19) S protein RBD, Fc Tag (MALS verified) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Phe 541 (Accession # QHD43416.1). Predicted N-terminus: Arg 319 This protein carries a human IgG1 Fc tag at the C-terminus.
- Pureté
- > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-MALS.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike S1 Protéine
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- Indications d'application
- The protein has a calculated MW of 51.5 kDa. The protein migrates as 58-65 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- For long term storage, the product should be stored at lyophilized state at -20°C or lower. This product is stable aftr storage at: -20°C to -70°C for 12 months in lyophilized state, -70°C for 3 months under sterile conditions after reconstitution.
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- Antigène
- SARS-CoV-2 Spike S1
- Abstract
- SARS-CoV-2 Spike S1 Produits
- Synonymes
- E2 Protein, Surface Glycoprotein Protein, S Protein
- Classe de substances
- Viral Protein
- Sujet
- It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Poids moléculaire
- 51.5 kDa
- ID gène
- 43740568
- UniProt
- P0DTC2
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