SARS-CoV-2 NSP7&NSP8, His Tag (NS8-C5125) is expressed from E.coli cells. It contains AA Ser 1 - Gln 83 (NSP7) & Ala 1 - Gln 198 (NSP8) (Accession # YP_009725303.1 (NSP7) & YP_009725304.1 (NSP8). Predicted N-terminus: Met This protein carries a polyhistidine tag.
Origine: SARS Coronavirus-2 (SARS-CoV-2)
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by Tris-Bis PAGE
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4
Stock
-80 °C
Stockage commentaire
The product MUST be stored at -70°C or lower upon receipt -70°C for 3 months under sterile conditions.
Antigène
SARS-CoV-2 NSP7, NSP8
Autre désignation
SARS-CoV-2 NSP7 & NSP8
Classe de substances
Viral Protein
Sujet
During the formation of the coronaviral replication/transcription complex, essential steps include processing of the conserved polyprotein nsp7-10 region by the main protease Mpro and subsequent complex formation of the released nsp's. Upon infecting host cells, coronaviruses assemble a multi-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replication and transcription of the viral genome. non-structural proteins 7 (NSP7) forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.