Mesothelin Protein (MSLN) (AA 296-580) (mFc-His Tag)
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- Antigène Voir toutes Mesothelin (MSLN) Protéines
- Mesothelin (MSLN)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 296-580
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Mesothelin protéine est marqué à la mFc-His Tag.
- Application
- Western Blotting (WB)
- Fonction
- Recombinant human Mesothelin(296-580) protein with C-terminal mouse Fc and 6xHis tag
- Specificité
- Mesothelin (Glu296-Gly580) mFc (Pro99-Lys330) 6xHis tag
- Attributs du produit
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Pureté
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product MSLN Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- Mesothelin (MSLN)
- Autre désignation
- Mesothelin (MSLN Produits)
- Synonymes
- MPF Protein, SMRP Protein, MSLN Protein, mesothelin Protein, MSLN Protein, Msln Protein, LOC611363 Protein, LOC100524016 Protein
- Sujet
- This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- Poids moléculaire
- predicted molecular mass of 59.3 kDa after removal of the signal peptide.
- ID gène
- 10232
- UniProt
- Q13421
- Pathways
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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