CD70 Protein (mFc-His Tag)

N° du produit ABIN6961112

Détail du produit

Antigène: CD70 (CD70 Molecule (CD70))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD70 protéine est marqué à la mFc-His Tag.

Application: ELISA

Fonction: Recombinant human CD70 protein with N-terminal mouse Fc and C-terminal 6xHis tag

Specificité: MFc (Pro99-Lys330) CD70 (Gln39-Pro193) 6xHis

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70 (CD70 Produits)

Sujet: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Poids moléculaire: predicted molecular mass of 45.6 kDa after removal of the signal peptide.

ID gène: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints