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CD8 alpha Protein (Fc Tag)

CD8A Origine: Humain Hôte: HEK-293 Cells Recombinant
N° du produit ABIN6964139
  • Antigène Voir toutes CD8 alpha (CD8A) Protéines
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Type de proteíne
    Recombinant
    Origine
    • 11
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain
    Source
    • 12
    • 7
    • 5
    • 3
    HEK-293 Cells
    Purification/Conjugué
    Cette CD8 alpha protéine est marqué à la Fc Tag.
    Séquence
    CD8A(Ser22-Asp182)+hFc(Glu99-Ala330)
    Attributs du produit
    Tagged Protein: C-Human Fc tag
    Purification
    affinity purification
    Top Product
    Discover our top product CD8A Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Agent conservateur
    Without preservative
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Date de péremption
    12 months
  • Antigène
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Autre désignation
    CD8A (CD8A Produits)
    Synonymes
    cd8 Protein, LOC100136450 Protein, BB154331 Protein, Ly-2 Protein, Ly-35 Protein, Ly-B Protein, Lyt-2 Protein, zgc:136643 Protein, CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, RHACD8-4 Protein, CD8a molecule Protein, uncharacterized LOC100125537 Protein, CD8 alpha Protein, CD8 antigen, alpha chain Protein, T-cell surface glycoprotein CD8 alpha chain Protein, Cd8a Protein, LOC100125537 Protein, LOC100136450 Protein, CD8A Protein, cd8a Protein, LOC100126556 Protein
    Sujet
    Synonymes: CD8, Leu2, p32
    Description: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein.
    Poids moléculaire
    43.23 kDa
    UniProt
    P01732
    Pathways
    TCR Signaling
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