C5AR1 Protein (AA 1-37) (Fc Tag)

N° du produit ABIN6964150

Détail du produit

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-37

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette C5AR1 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human C5AR1 Protein with C-terminal human Fc tag

Specificité: C5AR1 (Met1-Asp37) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Autre désignation: C5AR1 (C5AR1 Produits)

Synonymes: C5A Protein, C5AR Protein, C5R1 Protein, CD88 Protein, C5aR Protein, C5r1 Protein, Cd88 Protein, D7Msu1 Protein, GPR77 Protein, complement C5a receptor 1 Protein, complement component 5a receptor 1 Protein, C5AR1 Protein, C5ar1 Protein, c5ar1 Protein

Sujet: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.

Poids moléculaire: predicted molecular mass of 30.4 kDa after removal of the signal peptide.The apparent molecular mass of C5AR1-hFc is 40-53 kDa due to glycosylation.

UniProt: P21730

Pathways: Système du Complément