MMP11 Protein (AA 32-488) (Fc Tag)

N° du produit ABIN6964295

Détail du produit

Antigène: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Type de proteíne: Recombinant

Attributs du protein: AA 32-488

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MMP11 protéine est marqué à la Fc Tag.

Fonction: Recombinant human MMP11 protein with C-terminal human Fc tag

Specificité: MMP11 (Arg32-Leu488) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Autre désignation: MMP11 (MMP11 Produits)

Synonymes: SL-3 Protein, ST3 Protein, STMY3 Protein, Stmy3 Protein, MMP-11 Protein, matrix metallopeptidase 11 Protein, matrix metallopeptidase 11 L homeolog Protein, stromelysin-3 Protein, MMP11 Protein, Mmp11 Protein, mmp11.L Protein, LOC103694874 Protein

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 76.5 kDa after removal of the signal peptide.The apparent molecular mass of MMP11-hFc is 70-100 kDa due to glycosylation.

UniProt: P24347