SARS-CoV-2 Spike Protein (P.1 - gamma, RBD) (Fc Tag)
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- Antigène Voir toutes SARS-CoV-2 Spike Protéines
- SARS-CoV-2 Spike
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- P.1 - gamma, RBD
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Origine
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SARS-CoV-2 Spike protéine est marqué à la Fc Tag.
- Fonction
- SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), Fc Tag (MALS verified)
- Séquence
- AA 319-537
- Attributs du produit
- SARS-CoV-2 S protein RBD (K417T,E484K,N501Y), Fc Tag is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (K417T, E484K, N501Y). The K417T, E484K, N501Y mutations were identified in the SARS-CoV-2 variant (known as P.1) which emerged in Brazil.
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Stock
- -20 °C
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- Antigène
- SARS-CoV-2 Spike
- Autre désignation
- SARS-CoV-2 S protein (SARS-CoV-2 Spike Produits)
- Synonymes
- E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
- Classe de substances
- Viral Protein
- Sujet
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Poids moléculaire
- 51.1 kDa
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