KREMEN2 Protein (AA 26-364) (His tag)

N° du produit ABIN7013004

Détail du produit

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 26-364

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette KREMEN2 protéine est marqué à la His tag.

Fonction: Human Kremen-2 protein, His Tag

Pureté: >95 % as determined by reduced SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, 0.2M Arginine, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Autre désignation: KREMEN2 (KREMEN2 Produits)

Synonymes: krm2 Protein, KREMEN2 Protein, MGC147633 Protein, KRM2 Protein, 2900054E04Rik Protein, Krm2 Protein, kringle containing transmembrane protein 2 S homeolog Protein, kringle containing transmembrane protein 2 Protein, kremen2.S Protein, KREMEN2 Protein, kremen2 Protein, Kremen2 Protein

Sujet: Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer.

Poids moléculaire: 38.0 kDa

Pathways: Signalisation WNT