SARS-CoV-2 Spike S1 Protein (B.1.351 - beta, RBD) (His tag)
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- Antigène Voir toutes SARS-CoV-2 Spike S1 Protéines
- SARS-CoV-2 Spike S1
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- B.1.351 - beta, RBD
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Origine
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SARS-CoV-2 Spike S1 protéine est marqué à la His tag.
- Séquence
- AA 319-537
- Specificité
- SARS-CoV-2 (COVID-19) S protein RBD (K417N, E484K, N501Y), His Tag (MALS verified)
- Attributs du produit
- SARS-CoV-2 S protein RBD (K417N, E484K, N501Y), His Tag is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (K417N, E484K, N501Y). K417N / E484K / N501Y mutations were identified in the SARS-CoV-2 variant (known as 20C/501Y.V2 or B.1.351 lineage) which emerged in South Africa.
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike S1 Protéine
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- Indications d'application
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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An antigen microarray protocol for COVID-19 serological analysis." dans: STAR protocols, Vol. 2, Issue 3, pp. 100815, (2021) (PubMed).
: "
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An antigen microarray protocol for COVID-19 serological analysis." dans: STAR protocols, Vol. 2, Issue 3, pp. 100815, (2021) (PubMed).
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- Antigène
- SARS-CoV-2 Spike S1
- Autre désignation
- SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 Produits)
- Synonymes
- E2 Protein, Surface Glycoprotein Protein, S Protein
- Classe de substances
- Viral Protein
- Sujet
- It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Poids moléculaire
- 26.6 kDa
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