RNF43 Protein (AA 44-197) (Fc Tag)
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- Antigène Voir toutes RNF43 Protéines
- RNF43 (Ring Finger Protein 43 (RNF43))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 44-197
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette RNF43 protéine est marqué à la Fc Tag.
- Attributs du produit
- Human RNF43 Protein, Fc Tag (MALS verified)
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- RNF43 (Ring Finger Protein 43 (RNF43))
- Autre désignation
- RNF43 (RNF43 Produits)
- Synonymes
- RNF124 Protein, URCC Protein, 4732452J19Rik Protein, RGD1305204 Protein, ring finger protein 43 Protein, RNF43 Protein, Rnf43 Protein
- Sujet
- E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity)
- Poids moléculaire
- 43.5 kDa
- Pathways
- Signalisation WNT
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