SIGLEC7 Protein (AA 19-353) (His tag)

N° du produit ABIN7013595

Détail du produit

Antigène: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 19-353

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SIGLEC7 protéine est marqué à la His tag.

Séquence: AA 19-353

Attributs du produit: Biotinylated Human SIRP alphaV2 / CD172a Protein, His,Avitag™

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: MALS verified

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 25 mM MES, 150 mM NaCl, pH 5.5

Stock: -20 °C

Détail du antigène

Antigène: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Autre désignation: Siglec-7 (SIGLEC7 Produits)

Synonymes: SIGLEC7 Protein, AIRM1 Protein, CD328 Protein, CDw328 Protein, D-siglec Protein, QA79 Protein, SIGLEC-7 Protein, SIGLEC19P Protein, SIGLECP2 Protein, p75 Protein, p75/AIRM1 Protein, sialic acid-binding Ig-like lectin 7 Protein, sialic acid binding Ig like lectin 7 Protein, LOC468976 Protein, SIGLEC7 Protein

Sujet: Siglec-7 is a member of the human CD33-related Siglec receptor. The extracellular region of Siglec-7 is characterized by an N-terminal V-set Ig domain that can bind sialic acid and two C2-set Ig domains. The cytoplasmic tail of Siglec-7 has one immune-receptor tyrosine-based inhibitory motif (ITIM) and one ITIM-like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.

Poids moléculaire: 38.8 kDa

NCBI Accession: NP_055200