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Topoisomerase II alpha Protein (AA 1354-1473)

TOP2A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >90 % as determined by SDS-PAGE.
N° du produit ABIN7013599
  • Antigène Voir toutes Topoisomerase II alpha (TOP2A) Protéines
    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1354-1473
    Origine
    • 2
    • 1
    • 1
    Humain
    Source
    • 1
    • 1
    Escherichia coli (E. coli)
    Séquence
    AA 1354-1473
    Attributs du produit
    Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Protein, His Tag (MALS verified)
    Pureté
    >90 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product TOP2A Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    50 mM Tris, 0.5 M KCl, pH 8.0
    Stock
    -80 °C
  • Antigène
    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
    Autre désignation
    TOP2A (TOP2A Produits)
    Synonymes
    TOP2 Protein, TP2A Protein, TOP2A Protein, Top-2 Protein, TOP-2 Protein, F12B17.110 Protein, F12B17_110 Protein, thimet metalloendopeptidase 2 Protein, fc08c07 Protein, wu:fc08c07 Protein, DNA topoisomerase II alpha Protein, DNA topoisomerase II, alpha isozyme Protein, topoisomerase (DNA) II alpha Protein, Zincin-like metalloproteases family protein Protein, TOP2A Protein, Bm1_08705 Protein, Top2a Protein, AT5G10540 Protein, top2a Protein
    Sujet
    DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.
    Poids moléculaire
    12.8 kDa
    NCBI Accession
    NP_001058
    Pathways
    Cycle Cellulaire, Mitotic G1-G1/S Phases
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